. The proportion of responders was related to Enbrel dosage [see Clinical Studies (14.5)]. 2.2 Pediatric Patients Enbrel is administered by subcutaneous injection Etanercept 50 mg once weekly is an optimal dosage in most patients with RA. Increasing the dosage from 50 mg once weekly to 50 mg twice weekly in suboptimal responders did not significantly improve their DAS28 responses. Etanercept 50 mg once weekly is an optimal dosage in most patients with RA For adults with plaque psoriasis, the typical starting dosage (also called a loading dose) of Enbrel is 50 mg given twice a week for 3 months. Your doctor will start you at this higher dose to help..
In addition to the 50 mg twice weekly recommended starting dose, starting doses of 25 mg or 50 mg per week were shown to be efficacious. The proportion of responders was related to Enbrel dosage.. Clinical trials also used a maintenance dose of 25 mg subcutaneously given twice weekly. In addition to the 50 mg twice weekly recommended starting dose, starting doses of 25 mg or 50 mg per week were shown to be efficacious; however, the proportion of responders was related to the initial dosage. Subcutaneous dosage (Enbrel and Eticovo ONLY The long-term safety of etanercept for psoriasis is supported by a 96-week study of etanercept 50 mg twice weekly . Standard dosing for etanercept is 0.8 mg/kg Etanercept (Enbrel).
Main Menu ; About. Overview Amgen History Mission and Value Enbrel ® (etanercept) 168 INJECTIONS 6 Following twice weekly dosing for the first 3 months † ONE 50 mg injection per QW maintenance dose TNF INHIBITOR HUMIRA_1_YR Humira ® (adalimumab) 79 INJECTIONS 7 Following one 80 mg starter dose ONE 40 mg injection per QOW maintenance dose TNF INHIBITO
The recommended starting dose of ENBREL for adult patients is a 50 mg dose given twice weekly (administered 3 or 4 days apart) for 3 months followed by a reduction to a maintenance dose of 50 mg per week. A maintenance dose of 50 mg given twice weekly has also been shown to be efficacious The list price for ENBREL is $1,389.24 per weekly 50 mg dose.*,† For patients with moderate to severe plaque psoriasis, the recommended dose is 50 mg twice weekly for the first 3 months followed by 50 mg weekly thereafter. Most patients do not pay the list price. Your actual cost will vary based on your prescribed dosage and insurance coverage of Enbrel is 25 mg administered twice weekly. Alternatively, 50 mg given twice weekly may be used for up to 12 weeks followed, if necessary, by a dose of 25 mg twice weekly. This application was an extension application for a new 50 mg strength of Enbrel for use in adults with rheumatoid arthritis or plaque psoriasis according to the. No Yes. ×. Report. I take 50 mg Enbrel 2xweek, my derm said I will take the shot twice a week for the first 6 months and once a week for the second 6 months, during this year I will be closely monitored with blood draws and office visits every 3 months. My derm informed me that the risk of getting cancer is high already just because I have P. FOR IMMEDIATE RELEASE THOUSAND OAKS, Calif., Dec. 23, 2002 - Amgen (NASDAQ: AMGN) today announced that it has submitted a supplemental Biologics License Application (sBLA) with the U.S. Food and Drug Administration (FDA) supporting once-weekly dosing of ENBRELâ (etanercept)
Oct. 22, 2003 -- The FDA has approved the rheumatoid arthritis drug Enbrel for once-weekly dosing. Before now, Enbrel was only recommended as two 25 milligram injections three or four days apart... Medication Standard Limit FDA-recommended dosing Enbrel (etanercept) 25 mg per 0.5 mL prefilled syringe 8 syringes per 28 days RA/PsA/AS 50 mg every week PsO Loading dose: 50 mg twice a week for 3 months Maintenance dose: 50 mg every week Pediatric PsO/PJIA Weight < 63 kg: 0.8 mg per kg every week Weight ≥ 63 kg: 50 mg every week. Participants were to receive etanercept at a dose of 0.4 mg/kg twice weekly in Part 1A. Participants who had a partial response (not able to reduce prednisone dose by 50% of the baseline dose in 5 months) while on 0.4 mg/kg twice weekly etanercept in Part 1A were to enter Part 1B for up to 4 months and were to have the dose of etanercept increased to 0.8 mg/kg twice weekly I have to mix the enbrel and it is a bit of an involved process but the enbrel nurse was fantastic and talked me through each step. She will come again on Monday for the second one and hopefully after that I will have the hang of it
In addition to the 50 mg twice weekly recommended starting dose, starting doses of 25 mg or 50 mg per week were shown to be efficacious. The proportion of responders was related to Enbrel dosage [see Clinical Studies (14.5)]. 2.2 Pediatric Patients Enbrel is administered by subcutaneous injection. Table 2 All 8 children had increase in the etanercept dose to at least 0.8 mg/kg (mean 1.1 mg/kg, maximum 25 mg SC twice weekly) for a mean of 7 mo (range 3-10 mo). Efficacy of high dose etanercept was evaluated by changes in joint count, laboratory data, and ability to decrease concomitant medication
Objective To evaluate the safety and efficacy of long-term treatment of psoriasis with etanercept, 50 mg twice weekly.. Design, Setting, and Patients A phase 3, randomized, double-blind trial with an open-label extension. A total of 618 adult patients with moderate to severe plaque psoriasis were studied at 39 medical centers in the United States and Canada from May 23, 2003, through June 22. . However, if more than 48 hours have passed since the missed dose was due, do not make up that injection. Instead, simply wait until your next regularly scheduled dosing day and use the usual single dose Indication Dosing Regimen Maximum Dose RA 25 mg SC twice weekly or 50 mg SC once weekly 50 mg/week PsA AS 50 mg SC once weekly 50 mg/week Enbrel Mini TM single-dose prefilled cartridge for use with AutoTouch reusable autoinjector: 50 mg/mL . CLINICAL POLICY Etanercept Page 7 of 10 VII. Reference Etanercept (Enbrel ®) is now available in a prefilled syringe containing 50 mg/mL for once-weekly dosing for the treatment of rheumatoid arthritis (RA). The once-weekly is now the recommended dosing schedule in adult patients. However, the 25-mg twice-weekly formulation will still be available for patients with juvenile rheumatoid arthritis. once weekly. Enbrel may also be given twice weekly at a dose of 0.4 mg of Enbrel per kg bodyweight (up to amaximum of 25 mg). For psoriasis patients the recommended dose is 0.8 mg of Enbrel per kg bodyweight (up to a maximum of 50 mg) given once weekly. If Enbrel has no effect on the child's condition after 12 weeks, your doctor may tell yo
The recommended dose of ENBREL is 25 mg administered twice weekly or 50 mg administered once weekly. Alternatively, 50 mg given twice weekly may be used for up to 12 weeks followed, if necessary, by a dose of 25 mg twice weekly or 50 mg once weekly. Treatment with ENBREL should continue until remission is achieved, for up to 24 weeks ‡In medical studies, twice-weekly dosing for ENBREL ® was also shown to be effective in the first 12 weeks. ^Based on the recommended 300-mg dose. 150 mg may be acceptable for some patients. Of all the plaque psoriasis biologic medications, STELARA ® has the fewest yearly doses . In adults taking a placebo (a treatment without an.
The dose of etanercept (Enbrel) is 50 mg once weekly (as one subcutaneous injection using a 50 mg syringe or as two 25 mg injections given at approximately the same time) or 25 mg twice weekly (72 to 96 hours apart) as a subcutaneous injection • The recommended dose of Enbrel for adult individuals with RA, PsA, and ankylosing spondylitis is 50 mg per week by subcutaneous (SC) injection either as 50 mg once weekly or 25 mg twice weekly given 3 or 4 days apart. o The recommended dose in the treatment of JIA or pediatric plaque psoriasis is 0.8 mg/kg/week up to a maximum of 50 mg/week I currently take enbrel, and I've experienced a similar effect as you. My enbrel injection wears off a couple of days before my next injection. My doctor gave me the option to up the dose to twice a week (50 mg, not 25 2x), but warned that it does pack a double whammy for the immune system and leaves you at a much higher risk for infection
old) who were administered 0.4 mg/kg of Enbrel twice weekly for up to 18 weeks. For the treatment of moderate to severe psoriasis in children, it is intended to be administere Enbrel ® Etanercept (s.c.) injection administered in a dose of 50 mg twice weekly for the first 12 weeks. Enbrel ® Etanercept /GP2015 Etanercept 50 mg subcutaneous (s.c.) weekly injection of study drug until Week 30. Three periods of 6 weeks alternating between GP2015/Enbrel/GP2015 (Treatment Period 2) At the time, the standard dose of Enbrel for rheumatoid arthritis was twice-weekly injections. The heart-failure trial compared that and a three-times-a-week dose to a placebo The dosage can be adjusted to total 25-50 milligrams / week given twice but the maximum dosage must not exceed 50 mg/week. In the following months, the dosage should be kept to 50mg/ week. Enbrel is recommended only in case of adults receiving systemic therapy or phototherapy for treating chronic severe to moderate plaque (PsO) psoriasis Enbrel is given by injection under the skin. For adults, the usual recommended dose is 25 mg twice a week or 50 mg once a week. Treatment with 50 mg twice a week can also be used during the first 12 weeks of treatment for plaque psoriasis. For patients below 18 years of age, the dose depends on body weight
Judy - I did take my enbrel every other week, once I was feeling goodand I didn't notice any decrease in efficacy..some people are prescribed every other week anyhow. Sorry you are having a rough time with the side effects!! Julie - My daughter took them for 2 yrs twice a week and slowly reduced them over a yr taking half a tablet away. The recommended starting dose of BRENZYS for adult patients is a 50 mg dose given twice weekly (administered 3 or 4 days apart) for 3 months followed by a reduction to a maintenance dose of 50 mg per week. A maintenance dose of 50 mg given twice weekly has also been shown to be efficacious
Dosage for Enbrel. Enbrel is available in three preparations; 0.98 mL of a 50 mg/mL solution of etanercept, 0.51 mL of a 50 mg/mL solution of etanercept and 25 mg etanercept. patients reporting adverse reactions in the 50 mg twice a week dose group were similar to those observed in the 25 mg twice a week dose group or placebo group Since the prednisone didn't bring the disease under control, my RA doc decided he wants to keep me on Enbrel instead of changing because of other medical problems I have. I'll be taking 2 shots a week now, Monday & Thursday. I know some people take a lower does twice a week but didn't know you could take the higher dose twice a week
Enbrel vs Humira: they are similar, and fall into the same drug category (biologics), yet they are not identical. Here are the most common differences. — Enbrel. Enbrel can be taken up to twice a week, while the dosing schedule for Humira is much more patient specific. It is generally used once per week via a pre-filled syringe or auto. Inject SC into thigh, abdomen, or upper arm; rotate inj sites. ≥18yrs: initially 50mg twice weekly for 3 months (also: initial doses of 25mg or 50mg per week were shown to be efficacious. The recommended dose of ENBREL is 50 mg per week, given once weekly (single 50 mg injection) or twice weekly (single 25 mg injections given 3-4 days apart) as a subcutaneous injection. Higher responses may be achieved from initial treatment for up to 12 weeks with a dose of 50 mg given twice weekly, after which, the dose should be reduced to
The recommended starting dose of Erelzi for adult patients is a 50 mg dose given twice weekly (administered 3 or 4 days apart) for 3 months followed by a reduction to a maintenance dose of 50 mg per week. A maintenance dose of 50 mg given twice weekly has also been shown to be efficacious The dose of Erelzi to treat adult RA and PsA is 50 mg once weekly with or without methotrexate; the dose of Erelzi to treat AS is 50 mg once weekly; the dose of Erelzi to treat adult PsO is 50 mg twice weekly for 3 months, followed by 50 mg once weekly; and the dose of Erelzi to treat JIA (patients who weigh >63 kg) is 0.8 mg/kg weekly, with a. If you have psoriasis, the recommended starting dose of ENBREL for adult patients is a 50 mg dose twice a week (3 or 4 days apart) for 3 months. After 3 months, your doctor will tell you to reduce your dose to 50 mg once per week, using one 50 mg single-use prefilled syringe a. Prescriber will be dosing the patient within the FDA labeled maintenance dose of 50 mg weekly 3. Ankylosing Spondylitis (AS) a. Prescriber will be dosing the patient within the FDA labeled maintenance dose of 50 mg weekly AND ALL of the following: 1. Condition has improved or stabilized with Enbrel or biosimilar 2 Enbrel belongs to a group of drugs called tumor-necrosis factor (TNF) inhibitors, which help prevent inflammation. This medication comes in an injectable form and is injected under the skin (subcutaneously), usually once or twice a week. Common side effects include redness or pain at the injection site, upper respiratory infections, and headache
Subject: Enbrel Once-Weekly Dosing Will Help Neutralize Humira Advantage - Amgen Add a personalized message to your email. Cancel. Send. Please Note: Only individuals with an active subscription will be able to access the full article. All other readers will be directed to the abstract and would need to subscribe For juvenile idiopathic arthritis the recommended dose is 0.8 mg of Enbrel per kg bodyweight (up to a maximum of 50 mg) given once weekly. Enbrel may also be given twice weekly at a dose of 0.4 mg. The study examined the effectiveness of both 5 milligram and 10 milligram twice-daily doses of oral tofacitinib with a placebo and with the approved twice-weekly starting dose of injectable Enbrel The recommended dose is 25 mg given twice a week or 50 mg given once a week. Alternatively, 50 mg may be given twice a week for up to 12 weeks followed by 25 mg twice a week or 50 mg once a week. Your doctor will decide how long to take Enbrel and if resuming treatment is needed based on the treatment results Twice weekly dosing: 0.4 mg/kg/dose twice weekly given 72 to 96 hours apart Maximum dose: 25 mg Alternative once weekly dosing: 0.8 mg/kg/dose once weekly Maximum: 50 mg per week The 25 mg prefilled syringe is not recommended for pediatric patients weighing less than 31 kg (68 pounds)
How does Enbrel work. It is an arthritis-changing drug. It lowers swelling and helps lower signs and protect joints from more harm. It helps swelling. How should Enbrel be used. Adult- SC- The recommended dose is 50 mg weekly; twice weekly in plaque psoriasis. 0.8 mgkgweek in children Etanercept injection comes as a solution (liquid) in a prefilled syringe and an automatic injection device, and as a powder to be mixed with a provided liquid. Etanercept is injected subcutaneously (under the skin). It is usually injected once a week. When etanercept injection is used to treat chronic plaque psoriasis, it may be injected twice. . Etanercept (Enbrel), approved in the United States and in Europe for use in patients with RA and JRA, is an effective inhibitor of TNF that has been shown to provide rapid and sustained improvement in both of these diseases. comparing etanercept with methotrexate (median dose 20 mg per week). Both etanercept 25 mg twice weekly and rapidly.
STOT - repeated exposure: Even though this does not meet GHS classification, the following data is available: EnbrelÒ was administered in monkeys twice weekly at doses of 1, 1.5 or 15 mg/kg for 26 weeks. No significant effects were noted. Antibodies noted in all monkeys treated twice weekly for 26 weeks. However, no other adverse effects noted includes the preferred agents Enbrel (etanercept), Humira (adalimumab), Simponi mg weekly 50 mg twice for 3 , then 50 mg weekly JIA: 0.8 mg/kg weekly (max of 50 mg weekly) a loading dose per day, then 125 mg SC weekly for adults only. If no
with EU-approved Enbrel (scientific bridge) SC application once or twice a week depending on indication. drug substance, and final dosage form Quality System governed by Quality Assurance. ENBREL® should not be administered to patients with sepsis or with known hypersensitivity to ENBREL® or any of its components. Dosing (Adults): Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis: Once-weekly dosing: 50 mg once weekly . Twice weekly dosing: 25 mg given twice weekly (individual doses should be separated by 72-96. The recommended dosing regimen is 50mg per week or 25mg twice weekly. LU Authorization Period: 1 year . B. Ankylosing Spondylitis (Code 513) For the treatment of AS in patients who have severe active disease confirmed by radiographic Erelzi and Enbrel are both etanercept products. Etanercept is an anti-inflammatory medicin
A&E Mega-dosing vitamin D: Doctor-prescribed 50,000 IU vitamin D may be right for some patients. Thu., Nov. 1, 2018. Some health care providers are prescribing a mega-dose, 50,000 IU vitamin D. Once weekly wicT e weekly Twice weekly for 3 months; then once weekly 12-week supply 2-month supply 12-week supply-week supply Prolia® (denosumab) injection for Bone Health Shipped directly to the physician Repatha® (evolocumab) injection Sensipar® (cinacalcet) tablets UMAKRASTM (sotorasib) Enbrel® (etanercept
Dosing frequency and amounts vary based on the condition being treated. Generally, those being treated for rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis need an injection once a week. For children ages two to 17 who have juvenile idiopathic arthritis, injections are given once per week and the amount depends on weight patients treated with 50 mg ENBREL once weekly (n = 21); and 2.6 ± 1.2 mg/L, 1.4 ± 0.7 mg/L and 316 ± 135 mg.h/L for patients treated with 25 mg ENBREL twice weekly (n = 16). Serum concentrations in patients with RA have not been measured for periods of dosing that exceed 6 months
For plaque psoriasis, Enbrel is started at 50 mg twice a week for three months, after which it changes to the standard schedule. Pediatric dosage is based on weight and is 0.8 mg per kilogram (kg)—about 2.2 pounds—per week, not to exceed a maximum of 50 mg Enbrel® (etanercept) offers proven efficacy and an established safety profile. Find clinical trial data, dosing recommendations, administration options, patient support information, and more
Enbrel did not elicit dose-limiting or target organ toxicity in cynomolgus monkeys following twice weekly subcutaneous administration for 4 or 26 consecutive weeks at a dose (15 mg/kg) that resulted in AUC-based serum drug concentrations that were over 27-fold higher than that obtained in humans at the recommended dose of 25 mg Adults: 50 mg twice weekly for 3 months, followed by maintenance dose of 50 mg every week; b. Pediatrics (see Appendix E for dose rounding guidelines) (i or ii): o Enbrel should not be administered to patients with sepsis. • Definition of failure of MTX or DMARD Dosage . Enbrel is given by injection under the skin, which you (or a friend or family member) can do at home. It's available in pre-filled syringes, an auto-injector pen, or vials that you use to fill syringes. 50 mg twice a week for 3 months, then stepped down to once weekly: Psoriatic arthritis (adults) 50 mg per week . Enbrel is typically taken once to twice weekly and is injected subcutaneously into the fatty part of the skin. Enbrel blocks the actions of a receptor called TNF-alpha to reduce inflammation and relieve symptoms 50 mg) given once weekly. Enbrel may also be given twice weekly at a dose of 0.4 mg of Enbrel per kg bodyweight (up to a maximum of 25 mg). For psoriasis patients the recommended dose is 0.8 mg of Enbrel per kg bodyweight (up to a maximum of 50 mg) given once weekly. If Enbrel has no effect on the child's condition after 1
In a 12-week clinical study, the usual dosage is 5 mg taken by mouth twice a day. once or twice a day. Enbrel contains the drug etanercept. It's given as a subcutaneous (under the skin. No real downside: Tnf inhibitors like Enbrel don't increase in toxicity like other meds do. Increasing the dose to 50mg twice weekly is a good idea.But, if you don't also take methotrexate, for any reason, you will be more likely to develop antibodies against the Enbrel and neutralize it--causing it to lose most or all effectiveness.If increasing Enbrel does not work, consider another med like. The recommended dose is 0.4 mg/kg (up to a maximum of 25 mg per dose), given twice weekly as a subcutaneous injection with an interval of 3- 4 days between doses or 0.8 mg/kg (up to a maximum of 50 mg per dose) given once weekly. Discontinuation of treatment should be considered in patients who show no response after 4 months Enbrel is medication that is usually injected. Recommended weekly dose for psoriasis patients is 50mg. In most cases this dose is divided in two separate doses. So, as I can see your test article can not be done the way you imagine. Kids from your school can calculate daily dose, but Enbrel is not given daily. Try to write something else about. The patents received 50 milligrams of Enbrel twice a week. After the initial 12 weeks of treatment, 591 patients from both groups continued to receive Enbrel for 84 weeks
Patients were randomized to either 12 weeks of ENBREL 50 mg twice weekly followed by 12 weeks of ENBREL 50 mg once weekly (Group A), or 12 weeks of placebo twice weekly followed by 12 weeks of ENBREL 50 mg twice weekly (Group B). The primary endpoint was the mean percent improvement from baseline in PSSI at week 12 Enbrel Syringe dosing Usual Adult Dose for Ankylosing Spondylitis: 25 mg subcutaneously twice weekly, 3 to 4 days apart. Alternatively, 50 mg subcutaneous doses may be given once a week on the same day. Usual Adult Dose for Rheumatoid Arthritis: 25 mg subcutaneously twice weekly, 3 to 4 days apart By the way, a while back I was up to 8 pills of mtx a week and it made my RA symptoms almost disappear when combined with Enbrel. Unfortunately, I couldn't think straight on that dose and the nausea and fatigue were too bad, so I lowered it when I started the injections to .7 ml and now down to .6 ml. .6 is OK most days but not quite enough. Two 12-week trials compared the effectiveness of 50 mg of Enbrel given once weekly with that of 25 mg of Enbrel twice weekly. Both doses showed similar results in the measures of disease activity analyzed (ASAS20 response at week 12 was the primary goal), and acceptable safety
What are the side effects of abatacept? Donna Hill Howes, RN. Side effects may include headaches, inflammation of the nose and throat, upper respiratory infection. More Answers. What is fingolimod (Gilenya)? Multiple Sclerosis Foundation. Gilenya is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS) in adult ENBREL is indicated for reducing signs and symptoms, inducing major clinical response, inhibiting the progression of structural damage, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be initiated in combination with methotrexate (MTX) or used alone
TNF-α plays a central role in the pathogenesis of rheumatoid arthritis, and this lead to the development of anti-TNF therapy for rheumatoid arthritis. Etanercept (Enbrel, Immunex Corporation, Seattle, WA) is a recombinant dimer of human soluble p75 TNF receptor . So twice weekly subcutaneous dosing was selected on this basis. We initiated a. My wife was up to a month ago prescribe Enbrel injection twice weekly supplimented by 2 methetrexate tablets 1 x twice weekly. At christmas the doctor had to take her off Meth, due we think to bad side effects. Headaches, vomiting, nauses, stomach pains, tiredness, sleepy. Waiting to find out what the specialist says 25 mg twice weekly, alternatively 50 mg once weekly, review treatment if no response within 12 weeks of initial dose. Moderate-to-severe plaque psoriasis when the response to other systemic therapies or psoralen and ultraviolet-A light (PUVA) is inadequate, or when these therapies cannot be used because of intolerance or contra-indication
The results demonstrated that tofacitinib 10 mg twice daily had similar efficacy to high-dose ENBREL 50 mg twice weekly, said lead author Hervé Bachelez, M.D., Ph.D., Sorbonne Paris Cité. The results of OPT Compare showed that in a step-down procedure design, tofacitinib 10 mg twice daily (BID) was non-inferior to high-dose Enbrel (etanercept) 50 mg twice weekly (BIW), and tofacitinib 5 mg twice daily did not meet the non-inferiority criteria compared to high-dose Enbrel
The chart below illustrates the effect of two different dosing intervals on the amount of vitamin D3 in the blood. Daily dosing results in a fairly steady level of serum D3 with little fluctuation and risk for depletion, whereas weekly dosing (taking a single dose at 7 times the daily dose, once per week) causes a spike in vitamin D3 level, which then quickly drops and leaves the blood vitamin. 6. Dose does not exceed one of the following (a or b): a. Adults: 50 mg twice weekly for 3 months, followed by maintenance dose of 50 mg every week; b. Pediatrics (i or ii): i. Weight < 63 kg: 0.8 mg/kg per week; ii. Weight ≥ 63 kg: 50 mg per week. Approval duration: 6 months . F. Hidradenitis Suppurativa (off-label) (must meet all): 1.
Proven protection with a low median dose. The median doses used in AFSTYLA clinical trials were. 2x weekly. 35 IU/kg for patients of all ages. 3x weekly. 30 IU/kg for patients ≥12 years. 32 IU/kg for patients <12 years. §Annualized spontaneous bleeding rate in clinical trials (IQR=0-2.4 for patients ≥12 years; 0-2.2 for patients <12. Dosage: For treatment of RA, AS and PsA patients (Adults): Consider administration of 50 mg of Etanercept, every week; For treatment of PsO patients (Adults): Start with an initial dose of 50 mg twice weekly for three months. The maintenance dose can be 50 mg, once weekly. Precautions Etanercept is given as an injection under your skin. It is usually given once or twice a week. You may be given the injections by a nurse in your hospital clinic, or you may be taught how to give the injections to yourself. Your doctor or nurse will discuss these options with you. If you are given the injections to store at home, keep them in a. The dose of etanercept for plaque psoriasis is etanercept 50 mg twice a week (three or four days apart) for the first three months, followed by etanercept 50 mg once a week. Also, lower starting dosages (25 or 50 mg per week) have also been shown to be effective